Selective Release of Multiple DNA Oligonucleotides from Gold Nanorods

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Selective release of multiple DNA oligonucleotides from gold nanorods.

Combination therapy, or the use of multiple drugs, has been proven to be effective for complex diseases, but the differences in chemical properties and pharmacokinetics can be challenging in terms of the loading, delivering, and releasing multiple drugs. Here we demonstrate that we can load and selectively release two different DNA oligonucleotides from two different gold nanorods. DNA was load...

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Selective Light-Triggered Release of DNA from Gold Nanorods Switches Blood Clotting On and Off

Blood clotting is a precise cascade engineered to form a clot with temporal and spatial control. Current control of blood clotting is achieved predominantly by anticoagulants and thus inherently one-sided. Here we use a pair of nanorods (NRs) to provide a two-way switch for the blood clotting cascade by utilizing their ability to selectively release species on their surface under two different ...

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Selective nanodecoration of modified cyclodextrin crystals with gold nanorods.

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ژورنال

عنوان ژورنال: ACS Nano

سال: 2008

ISSN: 1936-0851,1936-086X

DOI: 10.1021/nn800702n